Hydrochloric Acid → HCID 178434511, compound

HRID 1792571Notes

Reaction equation

HRID 1792571 reaction equation
[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[C:9]3[C:14](=[CH:15][CH:16]=2)[N:13]=[CH:12][CH:11]=[C:10]3[N:17]2[CH:22]=[CH:21][N:20]([S:23]([NH2:26])(=[O:25])=[O:24])[CH:19]=[CH:18]2)=[CH:5][N:4](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[N:3]=1.Cl>>[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[C:9]3[C:14](=[CH:15][CH:16]=2)[N:13]=[CH:12][CH:11]=[C:10]3[N:17]2[CH:18]=[CH:19][N:20]([S:23]([NH2:26])(=[O:25])=[O:24])[CH:21]=[CH:22]2)=[CH:5][NH:4][N:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22031401HCID 22031401, compound

Product 1

HCID 178434511HCID 178434511, compoundYield 58%

Procedure

40 mg 4-[6-(3-methyl-1-trityl-1H-4-pyrazolyl)-4-quinolyl]-1-pyrazine sulfonamide obtained in Example 189 and 0.5 mL of 5 N hydrochloric acid were reacted in the same manner as in Example 162, to give 14 mg of the title compound as white crystals.

Sources & evidence

ORD record
ord-fb29228e8a37487cad26081daebb10c4
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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