Salicylic Acid → Salicylic acid monoethanolamine

HRID 1792734Notes

Reaction equation

HRID 1792734 reaction equation
[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:11]([CH2:13][NH2:14])[OH:12]>C(O)C>[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:11]([CH2:13][NH2:14])[OH:12]

Participants

4

Reactant 2

HCID 338Salicylic Acid3×HCID 700Ethanolamine3×

Product 1

HCID 3085170Salicylic acid monoethanolamine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a 100 ml glass, heat 50 g of ethyl alcohol (C16H34O) to 40° C. and maintain temperature. Slowly add, while stirring, 5 g of salicylic acid (C7H6O3) until dissolved. Add 2 g of monoethanolamine (C2H7NO) until completely mixed. Repeat above process of sequentially adding salicylic acid and monoethanolamine until a total of 20 g of salicylic acid and 8 g of monoethanolamine have been added. Remove heat source and allow to cool. After cooling, test pH of the compound. If pH is not equal to 7.0, slowly add monethanolamine until pH is equal to 7.0.

Workup

  1. temperaturemaintain temperature
  2. additionSlowly add
  3. additionuntil completely mixed
  4. customRemove
  5. temperatureheat source
  6. temperatureto cool
  7. temperatureAfter cooling

Sources & evidence

ORD record
ord-ab66ece575e14f4f88417ae953a68374
Source dataset
uspto-grants-2006_07
Patent number
US07078024B2

Reaction notes

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