Hydrochloric Acid → HCID 131725861, compound

HRID 1792851Notes

Reaction equation

HRID 1792851 reaction equation
C(OC(=O)[NH:7][CH2:8][C:9](=[O:21])[NH:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)(C)(C)C.[ClH:23]>O1CCOCC1>[Cl-:23].[NH2:7][CH2:8][C:9]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)=[O:21]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 69630702HCID 69630702, compound

Product 1

HCID 131725861HCID 131725861, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The crude [(4-phenyl-butylcarbamoyl)-methyl]-carbamic acid tert-butyl ester is stirred in a solution of dioxane (150 mL) and HCl (4 M dioxane, 42 mL, 168 mmol) for 17 h. The volatiles are removed in vacuo to provide 2-amino-N-(4-phenyl-butyl)-acetamide, hydrogen chloride salt which is used as is without further purification.

Workup

  1. customThe volatiles are removed in vacuo

Sources & evidence

ORD record
ord-7c03b28059c94baea3e7e6a4addbc311
Source dataset
uspto-grants-2006_07
Patent number
US07078425B2

Reaction notes

Loading…