Triethanolamine → HCID 11514448, compound

HRID 1793266Notes

Reaction equation

HRID 1793266 reaction equation
N(CCO)(CCO)CCO.[NH2:11][CH2:12][CH2:13][CH2:14][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1.F[C:21]1[CH:22]=[CH:23][C:24]([N+:28]([O-:30])=[O:29])=[C:25]([CH3:27])[CH:26]=1>CS(C)=O>[N+:28]([C:24]1[CH:23]=[CH:22][C:21]([NH:11][CH2:12][CH2:13][CH2:14][N:15]2[CH:19]=[CH:18][N:17]=[CH:16]2)=[CH:26][C:25]=1[CH3:27])([O-:30])=[O:29]

Participants

5

Reactant 3

HCID 7618TriethanolamineHCID 787361H-Imidazole-1-propanamineHCID 949565-Fluoro-2-nitrotoluene

Product 1

HCID 11514448HCID 11514448, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
80 °C

Procedure

150 ml of dimethyl sulfoxide were introduced into a 500 ml three-necked flask and treated with 22.6 g of triethanolamine (99% strength), 28.7 g of 1-(3-amino-propyl)imidazole (98% strength) and 24.2 g of 5-fluoro-2-nitrotoluene (96% strength). The mixture was stirred at 80° C. for 17 h. Following this, the batch was cooled to room temperature and poured onto 1 l of ice, a yellow oil depositing, which crystallized thoroughly after about 1 h. The precipitate thus resulting was filtered off with suction, washed with water and dried in vacuo at 40° C.

Workup

  1. temperaturewas cooled to room temperature
  2. customa yellow oil depositing, which crystallized thoroughly after about 1 h
  3. customThe precipitate thus resulting
  4. filtrationwas filtered off with suction
  5. washwashed with water
  6. customdried in vacuo at 40° C.

Sources & evidence

ORD record
ord-6c83fa214378440c89210958526a08e4
Source dataset
uspto-grants-2006_07
Patent number
US07081140B2

Reaction notes

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