Dimethylformamide → 5-[1-tert-butyl-2-(2-1,2,3-triazol-2-yl-phenyl)-1H-benzimidazol-5-yl]-pyrimidin-2-ylamine

HRID 179346Notes

Reaction equation

HRID 179346 reaction equation
[Br:1][c:2]1[c:3](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[C:13]([CH3:14])([CH3:15])[CH3:16])[cH:17][cH:18][c:19](-[c:21]2[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]2)[cH:20]3)[cH:4][cH:5][cH:6][cH:7]1.[C:33](=[O:34])([O-:35])[O-:36].[Cs+:37].[Cs+:38].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43].[nH:28]1[n:29][n:30][cH:31][cH:32]1>>[c:2]1(-[n:29]2[n:28][cH:32][cH:31][n:30]2)[c:3](-[c:8]2[n:9][c:10]3[c:11]([n:12]2[C:13]([CH3:14])([CH3:15])[CH3:16])[cH:17][cH:18][c:19](-[c:21]2[cH:22][n:23][c:24]([NH2:27])[n:25][cH:26]2)[cH:20]3)[cH:4][cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 585419535-[2-(2-bromo-phenyl)-1-tert-butyl-1H-benzimidazol-5-yl]-pyrimidin-2-ylamineHCID 178418936HCID 178418936, compound

Product 1

HCID 532362545-[1-tert-butyl-2-(2-1,2,3-triazol-2-yl-phenyl)-1H-benzimidazol-5-yl]-pyrimidin-2-ylamine

Sources & evidence

ORD record
ord-4b4e888ff1ee4ab5a399cba4ddb73f61
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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