HCID 2756143, compound → HCID 69140874, compound

Participants

Reaction Steps

Prepared in analogy to piperazine-1,4-dicarboxylic acid 4-benzyloxy-benzyl ester 9H-fluoren-9-ylmethyl ester (Example 41) from (RS)-carbonic acid 1-chloro-ethyl ester 4-(4-fluoro-benzyloxy)-benzyl ester) and N-Fmoc-piperazine: yellow solid. 1H-NMR (CDCl3): 3.3–3.6 m, 8H; 4.23 t, J=6 Hz, 1H; 4.48 d, J=6 Hz, 2H; 5.03 s, 2H; 5.08 s, 2H; 6.95 d, J=8.5 Hz, 2H, 7.08 t, J=8.5 Hz, 2H, 7.25–7.46 m, 8H, 7.55 d, J=7 Hz, 2H and 7.77 d, J=7 Hz, 2H.

Provenance & Evidence