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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1794077Generated: October 25, 2026

Tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate → HCID 86585997, compound

https://huagongshe.com/reaction/1794077

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylateHCID 11334154—
Reactanttert-Butyl (2R,6S)-2,6-dimethylpiperazine-1-carboxylateHCID 21021901—
ProductHCID 86585997HCID 86585997—

Reaction Steps

cis-4-chlorocarbonyl-2,6-dimethyl-piperazine-1-carboxylic acid tert-butyl ester was prepared in analogy to 4-chlorocarbonyl-piperazine-1-carboxylic acid tert-butyl ester from cis-2,6-dimethylpiperazine-1-carboxylic acid tert-butyl ester (A. Muehlebach, P. Pino, Helv. Chim. Acta 73, 839 (1990)) by a modified procedure of Rhone-Poulenc DE 25 50 111 (Rhone-Poulenc).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07022707B2
Source datasetuspto-grants-2006_04
ORD IDord-41fc49f75aca4d0caca7af49448107a0
Source noteuspto-grants-2006_04