HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)-2-methyl-1,3-thiazole → 2,6-Difluoro-4-[(2-methyl-4-thiazolyl)methoxy]benzenemethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)-2-methyl-1,3-thiazole | HCID 736341 | — |
| Reactant | 3,5-Difluoro-4-(hydroxymethyl)phenol | HCID 22219975 | — |
| Product | 2,6-Difluoro-4-[(2-methyl-4-thiazolyl)methoxy]benzenemethanol | HCID 22219955 | 73% |
Reaction Steps
This compound was prepared from 3,5-difluoro-4-hydroxymethyl-phenol and 4-chlormethyl-2-methylthiazol according to the procedure described in Example 179 to give the product as a colorless oil (369 mg, 73%); MS (ISP): 272.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07022707B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-d1e7f5499b5c414ebae3b44093005352 |
| Source note | uspto-grants-2006_04 |