Butyl bromide → HCID 10144147, compound

HRID 1794202Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[Cl:11][C:12]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:13]=1[CH:14]=O.Br[CH2:22][CH2:23][CH2:24][CH3:25]>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4]([CH:14]([C:4]1[C:3]3[C:7](=[CH:8][CH:9]=[CH:10][C:2]=3[Cl:1])[N:6]([CH2:10][CH2:2][CH2:3][CH3:4])[CH:5]=1)[C:13]1[CH:16]=[CH:17][C:18]([F:20])=[CH:19][C:12]=1[Cl:11])=[CH:5][N:6]2[CH2:22][CH2:23][CH2:24][CH3:25]

Participants

Reactant 3

HCID 8002Butyl bromide

HCID 913454-Chloroindole

HCID 1450242-Chloro-4-fluorobenzaldehyde

Product 1

HCID 10144147HCID 10144147, compound

Procedure

The compound Bis(4-chloro-1-butylindol-3-yl)-(2-chloro-4-fluorophenyl)methane was prepared following procedure A, starting from 4-chloro indole and 2-chloro 4-fluorobenzaldehyde, and the resulting compound was reacted with 1-bromobutane following procedure B. LC: Tr 2.83 min, MS: 555 (M+H)+

Workup

customTr 2.83 min, MS

Sources & evidence

ORD record: ord-ab843102f90e4e25abe870a8c71914ca
Source dataset: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07022730B2

Reaction notes

Loading…