Benzyl Bromide → HCID 10121911, compound

HRID 1794203Notes

Reaction equation

HRID 1794203 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[Cl:11][C:12]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:13]=1[CH:14]=O.[CH2:21](Br)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4]([CH:14]([C:4]1[C:3]3[C:7](=[CH:8][CH:9]=[CH:10][C:2]=3[Cl:1])[N:6]([CH2:4][C:3]3[CH:7]=[CH:8][CH:9]=[CH:10][CH:2]=3)[CH:5]=1)[C:13]1[CH:16]=[CH:17][C:18]([F:20])=[CH:19][C:12]=1[Cl:11])=[CH:5][N:6]2[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 913454-ChloroindoleHCID 1450242-Chloro-4-fluorobenzaldehyde

Product 1

HCID 10121911HCID 10121911, compound

Procedure

The compound Bis(4-chloro-1-benzylindol-3-yl)-(2-chloro-4-fluorophenyl)methane was prepared following procedure A, starting from 4-chloro indole and 2-chloro 4-fluorobenzaldehyde, resulted compound was reacted with benzyl bromide following procedure B. LC: Tr 2.94 min, MS: 623 (M+H)+

Workup

  1. customresulted compound
  2. customTr 2.94 min, MS

Sources & evidence

ORD record
ord-33cde9dbcf624907856db5cd70e0fee8
Source dataset
uspto-grants-2006_04
Patent number
US07022730B2

Reaction notes

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