反应详情

In a preferred method of preparing F-Dopa, 2-fluoro-4,5-dimethoxybenzaldehyde is reacted with tert-Butoxycarbonylamino-(dimethoxy-phosphoryl)-acetic acid ethyl ester to produce 2-tert-butoxycarbonylamino-3-(2-fluoro-4,5-dimethoxy-phenyl)-acrylic acid ethyl ester. In this method R is methyl, R1 is methoxy, X is fluorine, R2 is methyl, and Y is tert-butoxycarbonyl.