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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1795489Generated: October 31, 2026

Hydrochloric Acid → HCID 12084911, compound

https://huagongshe.com/reaction/1795489

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantHCID 69599570HCID 69599570—
SolventTetrahydrofuranHCID 8028—
ProductHCID 12084911HCID 1208491192%

Reaction Steps

In tetrahydrofuran (35 mL) was dissolved (4R)-2-(benzyloxycarbonyl)amino-5-(2,4-difluorophenyl)-4-methyl-5-hydroxyoxazolidine (6.98 g) prepared in Example 16, and water (25 mL) and conc. hydrochloric acid (10 mL) were added. The mixture was processed as described in Example 13 to give the title compound (5.87 g) as pale yellow syrup in a yield of 92%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07026515B2
Source datasetuspto-grants-2006_04
ORD IDord-c71fe44ae1114e1686959862dc7d12c5
Source noteuspto-grants-2006_04