1-Iodopropane → HCID 22218326, compound

HRID 1795616Notes

Reaction equation

HRID 1795616 reaction equation
[Br:1][C:2]1[C:3]([OH:17])=[CH:4][C:5]2[C:6]([CH3:16])([CH3:15])[CH2:7][CH:8]=[C:9]([CH:12]([CH3:14])[CH3:13])[C:10]=2[CH:11]=1.I[CH2:19][CH2:20][CH3:21]>>[Br:1][C:2]1[CH:11]=[C:10]2[C:5](=[CH:4][C:3]=1[O:17][CH2:19][CH2:20][CH3:21])[C:6]([CH3:15])([CH3:16])[CH2:7][CH:8]=[C:9]2[CH:12]([CH3:13])[CH3:14]

Participants

3

Reactant 2

HCID 336431-IodopropaneHCID 22218215HCID 22218215, compound2×

Product 1

HCID 22218326HCID 22218326, compoundYield 70%

Procedure

Following General Procedure O, 3-bromo-5-isopropyl-8,8-dimethyl-7,8-dihydronaphthalen-2-ol (Compound 97, 0.36 g, 1.2 mmol) was reacted with 1-iodopropane to afford 0.29 g (70%) of the title compound as a clear oil.

Sources & evidence

ORD record
ord-8a95eb90b35844f8b7acf1a0a72a4b2c
Source dataset
uspto-grants-2006_04
Patent number
US07026487B2

Reaction notes

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