Benzyl Bromide → HCID 22218255, compound
Reaction equation
[Br:1][C:2]1[C:3]([OH:17])=[CH:4][C:5]2[C:6]([CH3:16])([CH3:15])[CH2:7][CH:8]=[C:9]([CH:12]([CH3:14])[CH3:13])[C:10]=2[CH:11]=1.[CH2:18](Br)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([O:17][C:3]1[CH:4]=[C:5]2[C:10]([C:9]([CH:12]([CH3:13])[CH3:14])=[CH:8][CH2:7][C:6]2([CH3:15])[CH3:16])=[CH:11][C:2]=1[Br:1])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1Participants
3
Procedure
Following General Procedure O, 3-bromo-5-isopropyl-8,8-dimethyl-7,8-dihydronaphthalen-2-ol (Compound 97, 0.29 g, 0.98 mmol) was reacted with benzylbromide to afford 0.38 g (100%) of the title compound as a yellow oil.
Sources & evidence
- ORD record
- ord-7e18e800cbb14e309a9bacfeabf2ba94
- Source dataset
- uspto-grants-2006_04
- Patent number
- US07026487B2
Reaction notes
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