Benzyl Bromide → HCID 22218284, compound

HRID 1795625Notes

Reaction equation

HRID 1795625 reaction equation
[Br:1][C:2]1[C:3]([OH:18])=[CH:4][C:5]2[C:6]([CH3:17])([CH3:16])[CH2:7][CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=2[CH:11]=1.[CH2:19](Br)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:19]([O:18][C:3]1[CH:4]=[C:5]2[C:10]([C:9]([C:12]([CH3:13])([CH3:15])[CH3:14])=[CH:8][CH2:7][C:6]2([CH3:17])[CH3:16])=[CH:11][C:2]=1[Br:1])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 22218257HCID 22218257, compound2×

Product 1

HCID 22218284HCID 22218284, compoundYield 100%

Procedure

Following General Procedure O, 3-bromo-5-t-butyl-8,8-dimethyl-7,8-dihydronaphthalen-2-ol (Compound 98, 0.18 g, 0.58 mmol) was reacted with benzyl bromide to afford 0.23 g (100%) of the title compound as a yellow oil.

Sources & evidence

ORD record
ord-42a5b166ce2f4e5f8131447f3cf22d6c
Source dataset
uspto-grants-2006_04
Patent number
US07026487B2

Reaction notes

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