2,6-Dibromopyridine → HCID 9945633, compound

Participants

Reaction Steps

2,6-Dibromopyridine was coupled with 7-(1-fluoro-1-methylethyl)-3-tributylstannylimidazo[1,2-α]pyrimidine by the method of Example 1 to afford 3-(6-bromopyridin-2-yl)-7-(1-fluoro-1-methylethyl)imidazo[1,2-α]pyrimidine (1.0 g, 68%) as a pale yellow solid: δH (360 MHz, CDCl3) 1.81 (6H, d, J 22), 7.37 (1H, d, J 8), 7.42 (1H, dd, J 7 and 2), 7.61 (1H, dd, J 8 and 8), 7.71 (1H, dd, J 8 and 1), 8.33 (1H, s), 10.09 (1H, d, J 7).

Provenance & Evidence