HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazo[1,2-a]pyrimidine, 3-(tributylstannyl)-7-(trifluoromethyl)- → HCID 9924936, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazo[1,2-a]pyrimidine, 3-(tributylstannyl)-7-(trifluoromethyl)- | HCID 11294484 | — |
| Reactant | 5-Bromo-2-(4-fluorophenyl)pyridine | HCID 22180779 | — |
| Product | HCID 9924936 | HCID 9924936 | — |
Reaction Steps
3-Tributylstannyl-7-trifluoromethylimidazo[1,2-α]pyrimidine was reacted with 5-bromo-2-(4-fluorophenyl)pyridine by the method of Example 1 to furnish 3-[2-(4-fluorophenyl)pyridin-5-yl]-7-trifluoromethylimidazo[1,2-α]pyrimidine (47mg) as a yellow solid: δH (400 MHz, CDCl3) 7.19-7.25 (2H, m), 7.31 (1H, d, J 7), 7.90-7.97 (2H, m), 8.06-8.11 (2H, m), 8.19 (1H, s), 8.82 (1H, d, J 7), 8.91 (1H, dd, J 2 and 1); m/z (ES+) 358, 359 (M++H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07030128B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-4b3eca8c95d24a0992ffb5f54304bc08 |
| Source note | uspto-grants-2006_04 |