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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796156Generated: November 1, 2026

(R)-2-((S)-1-Hydroxy-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid → (S)-2-(1-Fluoro-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid

https://huagongshe.com/reaction/1796156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-((S)-1-Hydroxy-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acidHCID 58619483—
Reactant(S)-2-(1-Fluoro-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid methyl esterHCID 69619069—
Product(S)-2-(1-Fluoro-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acidHCID 58619495—

Reaction Steps

It is similarly prepared according to the procedure of (22), but using (S)-2-(1-Fluoro-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid methyl ester (6a).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030116B2
Source datasetuspto-grants-2006_04
ORD IDord-a1d59dfb4a4648dc89d2174a40c439b4
Source noteuspto-grants-2006_04