HRID1796163

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)C(CC(=O)N1CCOCC1)CS(=O)(=O)Cc1ccccc1

HCID22053987

未命名化合物

结构：CCC(N)[C@H](O)c1noc(C(F)(F)F)n1.O=C(O)C(F)(F)F

HCID86588340

未命名化合物

PRODUCTS

生成物

结构：CC[C@H](NC(=O)C(CC(=O)N1CCOCC1)CS(=O)(=O)Cc1ccccc1)C(=O)c1noc(C(F)(F)F)n1

HCID58619528

未命名化合物

PROCEDURE

实验过程

It is similarly prepared according to general procedure given for Example 2 above but using 4-Morpholin-4-yl-4-oxo-2-phenylmethanesulfonylmethyl-butyric acid and (S)-2-Amino-1-(5-trifluoromethyl-1,2,4-oxadiazol-3-yl)-butan-1-ol; compound with trifluoroacetic acid.

WORKUP

后处理

customIt is similarly prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9d6d8e404f0e43df98e3d59576e9802c
来源数据集: uspto-grants-2006_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07030116B2
来源说明: uspto-grants-2006_04

反应 SMILES

[N:1]1([C:7](=[O:24])[CH2:8][CH:9]([CH2:13][S:14]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)(=[O:16])=[O:15])[C:10]([OH:12])=O)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.FC(F)(F)C(O)=O.[NH2:32][CH:33]([CH2:45][CH3:46])[C@@H:34]([C:36]1[N:40]=[C:39]([C:41]([F:44])([F:43])[F:42])[O:38][N:37]=1)[OH:35]>>[N:1]1([C:7](=[O:24])[CH2:8][CH:9]([CH2:13][S:14]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)(=[O:16])=[O:15])[C:10]([NH:32][C@H:33]([C:34]([C:36]2[N:40]=[C:39]([C:41]([F:44])([F:43])[F:42])[O:38][N:37]=2)=[O:35])[CH2:45][CH3:46])=[O:12])[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1