HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-(1-Benzyl-cyclopropylmethyl)-4-morpholin-4-yl-4-oxo-butyric acid → (R)-2-(1-Benzyl-cyclopropylmethyl)-N-[(S)-1-(5-ethyl-1,2,4-oxadiazole-3-carbonyl)-propyl]-4-morpholin-4-yl-4-oxo-butyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-(1-Benzyl-cyclopropylmethyl)-4-morpholin-4-yl-4-oxo-butyric acid | HCID 58619525 | — |
| Reactant | (S)-2-amino-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-butan-1-ol trifluoroacetate | HCID 69427127 | — |
| Product | (R)-2-(1-Benzyl-cyclopropylmethyl)-N-[(S)-1-(5-ethyl-1,2,4-oxadiazole-3-carbonyl)-propyl]-4-morpholin-4-yl-4-oxo-butyramide | HCID 58619522 | — |
Reaction Steps
It is similarly prepared according to general procedure given for example 10 above but using (R)-2-(1-Benzyl-cyclopropylmethyl)-4-morpholin-4-yl-4-oxo-butyric acid and (S)-2-Amino-1-(5-ethyl-1,2,4-oxadiazol-3-yl)-butan-1-ol; compound with trifluoro-acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07030116B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-ce6e55d3cce14f69b4d6aabba8c28512 |
| Source note | uspto-grants-2006_04 |