HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (r)-2-((s)-1-Hydroxy-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid[(s)-1-(oxazole-2-carbonyl)-propyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (R)-2-((S)-1-Hydroxy-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid | HCID 58619483 | — |
| Reactant | (S)-2-Amino-1-oxazol-2-yl-butan-1-one | HCID 58619524 | — |
| Product | (r)-2-((s)-1-Hydroxy-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid[(s)-1-(oxazole-2-carbonyl)-propyl]-amide | HCID 58619488 | — |
Reaction Steps
It is similarly prepared according to the general procedure for Example 10 using (S)-2-Amino-1-oxazol-2-yl-butan-1-one; hydrochloride as the amino component and (R)-2-((S)-1-Hydroxy-2-morpholin-4-yl-2-oxo-ethyl)-5-phenyl-pentanoic acid as the acidic component but without further oxidation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07030116B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-3e4f540577da48e2bade08911a53c8ba |
| Source note | uspto-grants-2006_04 |