HRID1796292

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CO[C@@H]1C[C@H](C(=O)Nc2ccc(-n3ccc(C)n3)cc2F)N(C(=O)OC(C)(C)C)C1

HCID68805326

未命名化合物

PRODUCTS

生成物

结构：CO[C@H]1CN[C@@H](C(=O)Nc2ccc(-n3ccc(C)n3)cc2F)C1

HCID69737392

未命名化合物

收率 99.1%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

溶剂HCID6422

未命名化合物

PROCEDURE

实验过程

Boc-amine 3 (˜0.6 g, 1.427 mmol) was dissolved in 25% TFA in dichloromethane. The mixture was stirred at ambient temperature for 2 h. The solvents were removed and the residue dried under vacuum to give 4 as a tan oil (˜0.450 g).

WORKUP

后处理

customThe solvents were removed
customthe residue dried under vacuum