HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 23706078, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | [(Thiophene-2-carbonyl)amino] acetic acid methyl ester | HCID 531395 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 23706078 | HCID 23706078 | 103.8% |
Reaction Steps
To 200 ml of a solution of 16.70 g of methyl 2-(2-thenoylamino)acetate in methanol, 20 ml of aqueous solution of 4.02 g sodium hydroxide was added, and heated to reflux for 30 minutes. The solvent was distilled off under reduced pressure. The residue was crystallized by addition of isopropanol to provide 18.03 g of the objective compound as pale yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07030143B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-b9617518d6cb43daab999e2a75aa624d |
| Source note | uspto-grants-2006_04 |