HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796457Generated: November 2, 2026
Methylamine hydrochloride → HCID 22181383, compound
https://huagongshe.com/reaction/1796457
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine hydrochloride | HCID 6364545 | — |
| Reactant | N,N-diethyl-4-fluoro-3-nitrobenzamide | HCID 22181444 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 22181383 | HCID 22181383 | 100% |
Reaction Steps
Following general procedure 2B: A mixture of N,N-diethyl-4-fluoro-3-nitrobenzamide (0.125 g, 0.521 mmol), methylamine hydrochloride (0.035 g, 0.521 mmol) in 80% aq. EtOH (3 mL) was heated at 85° C. for 4 hours. Usual work-up provided the title compound (0.130 g, 100%) which was used without further purification. MS (ESI) (M+H)+=252.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07030139B2 |
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| Source dataset | uspto-grants-2006_04 |
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| ORD ID | ord-23425a4915a346afb4564aec7cc3c34a |
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| Source note | uspto-grants-2006_04 |
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