HCID 21025053, compound → HCID 21025054, compound

Participants

Reaction Steps

[4-(4-Benzyloxy-phenylamino)-3-cyano-5-methyl-pyrrolo[1,2-b]pyridazin-6-yl]-carbamic acid 2-morpholin-4-yl-ethyl ester 380C (0.79 mmol, 420 mg) and 10% Pd(C) (180 mg) in DMF (10 ml) were stirred under H2 gas (1 atm) for 24 hours. The reaction mixture was filtered to afford 380D as a yellow solid (320 mg, 92%). [M+H]+=437.21.

Provenance & Evidence