Acetic Anhydride → HCID 9902340, compound

HRID 1796691Notes

Reaction equation

HRID 1796691 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[NH:9][C@@H:8]([CH3:13])[CH2:7][C@H:6]2[NH:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH3:22])=[CH:17][CH:16]=1)[CH3:2].[C:23](OC(=O)C)(=[O:25])[CH3:24]>N1C=CC=CC=1>[C:23]([N:9]1[C:10]2[C:5](=[CH:4][C:3]([CH2:1][CH3:2])=[CH:12][CH:11]=2)[C@H:6]([NH:14][C:15]2[CH:16]=[CH:17][C:18]([CH2:21][CH3:22])=[CH:19][CH:20]=2)[CH2:7][C@@H:8]1[CH3:13])(=[O:25])[CH3:24]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 69585333HCID 69585333, compound

Product 1

HCID 9902340HCID 9902340, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The compound of Step 1 (59 mg, 0.20 mmol) was dissolved in pyridine (1 ml) and acetic anhydride (2.0 mmol) was added. After stirring at room temperature for 20 hours the solvent was evaporated and the crude product was purified on silica (ethyl acetate:heptane 1:2). The title compound was obtained as a colorless oil (0.12 mmol).

Workup

  1. customwas evaporated
  2. customthe crude product was purified on silica (ethyl acetate:heptane 1:2)

Sources & evidence

ORD record
ord-2221c78f08b94448b96d71efe65a94e3
Source dataset
uspto-grants-2006_04
Patent number
US07030246B2

Reaction notes

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