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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796776Generated: November 2, 2026

7-piperazinyl-2-(pyridin-2-yl)methyl-2H-phthalazin-1-one → 2-(Pyridin-2-yl)methyl-7-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]-2H-phthalazin-1-one

https://huagongshe.com/reaction/1796776

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-piperazinyl-2-(pyridin-2-yl)methyl-2H-phthalazin-1-oneHCID 22180293—
Reactant3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl bromideHCID 22180583—
Product2-(Pyridin-2-yl)methyl-7-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]-2H-phthalazin-1-oneHCID 22180455—

Reaction Steps

Step (b) of Example 92 was repeated, except that the compound prepared in step (b) of Example 114 and the compound prepared in step (c) of Example 143 were used as the starting compounds. Thus, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030120B2
Source datasetuspto-grants-2006_04
ORD IDord-0e9f8e1cad864c82acb326cf83a4082b
Source noteuspto-grants-2006_04