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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1796782Generated: November 2, 2026

3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl bromide → ethyl 2-methyl-3-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]benzoate

https://huagongshe.com/reaction/1796782

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl bromideHCID 22180583—
ReactantEthyl 2-methyl-3-piperazin-1-ylbenzoateHCID 22180591—
Productethyl 2-methyl-3-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]benzoateHCID 22180646—

Reaction Steps

Step (b) of Example 1 was repeated, except that the compound prepared in step (a) of Example 53 and the compound prepared in step (b) of Example 114 were used as the starting compounds. Thus, ethyl 2-methyl-3-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]benzoate was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07030120B2
Source datasetuspto-grants-2006_04
ORD IDord-5a44142f599645e58aecd2b8732a4461
Source noteuspto-grants-2006_04