1-Phenylpyrrole → 2-[(2-Methoxyphenyl)-pyrrolidin-1-yl-methyl]-1-phenyl-1H-pyrrole
Reaction equation
[C:1]1([N:7]2[CH:11]=[CH:10][CH:9]=[CH:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl-].[CH3:13][O:14][C:15]1[CH:26]=[CH:25][CH:24]=[CH:23][C:16]=1[CH:17]=[N+:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH3:13][O:14][C:15]1[CH:26]=[CH:25][CH:24]=[CH:23][C:16]=1[CH:17]([N:18]1[CH2:22][CH2:21][CH2:20][CH2:19]1)[C:8]1[N:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH:11]=[CH:10][CH:9]=1Participants
3
Procedure
The preparation was carried out in accordance with general synthesis instructions 4 from 1-phenyl-1H-pyrrole and 1-(2-methoxy-benzylidene)pyrrolidinium chloride.
Sources & evidence
- ORD record
- ord-0f8691cafb7549518380cdafec3b7da2
- Source dataset
- uspto-grants-2006_04
- Patent number
- US07034018B2
Reaction notes
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