HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 3-{2-[(2-Fluoro-phenyl)-piperidin-1-yl-methyl]-pyrrol-1-yl}-propionitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | o-Fluorobenzaldehyde | HCID 67970 | — |
| Reactant | 3-(Pyrrol-1-yl)propiononitrile | HCID 96527 | — |
| Reactant | 1-(2-Fluoro-benzylidene)-piperidinium chloride | HCID 17912301 | — |
| Product | 3-{2-[(2-Fluoro-phenyl)-piperidin-1-yl-methyl]-pyrrol-1-yl}-propionitrile | HCID 9857895 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 3-pyrrol-1-yl-propionitrile and 1-(2-fluoro-benzylidene)-piperidinium chloride, which had been prepared in accordance with example 3 from 2-fluorobenzaldehyde and piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07034018B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-7caf6ae5c4664fdda083e12347e3fb7b |
| Source note | uspto-grants-2006_04 |