HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 1-[[1-(2-Chloro-ethyl)-1H-pyrrol-2-yl]-(4-fluoro-phenyl)-methyl]-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | 1-(2-Chloroethyl)pyrrole | HCID 12674170 | — |
| Reactant | 1-(4-Fluorobenzylidene)-piperidinium chloride | HCID 17912261 | — |
| Product | 1-[[1-(2-Chloro-ethyl)-1H-pyrrol-2-yl]-(4-fluoro-phenyl)-methyl]-piperidine | HCID 9944954 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 2-pyrrol-1-yl-chloroethane and 1-(4-fluoro-benzylidene)-piperidinium chloride, which had been prepared in accordance with example 3 from 4-fluorobenzaldehyde and piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07034018B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-e56524f4d62f429fb447e1b585626b7e |
| Source note | uspto-grants-2006_04 |