HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 3-{2-[(4-Fluoro-phenyl)-piperidin-1-yl-methyl]-pyrrol-1-yl}-propan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | 1-(3-Hydroxypropyl)pyrrole | HCID 12794991 | — |
| Reactant | 1-(4-Fluorobenzylidene)-piperidinium chloride | HCID 17912261 | — |
| Product | 3-{2-[(4-Fluoro-phenyl)-piperidin-1-yl-methyl]-pyrrol-1-yl}-propan-1-ol | HCID 9901483 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 3-pyrrol-1-yl-propanol and 1-(4-fluorobenzylidene)-piperidinium chloride, which had been prepared in accordance with example 3 from 4-fluorobenzaldehyde and piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07034018B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-5d092fd551954438aae235b0d58a74ab |
| Source note | uspto-grants-2006_04 |