HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 2-{2-[(5-Bromo-2-fluoro-phenyl)-pyrrolidin-1-yl-methyl]-pyrrol-1-yl}-thiobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 5-Bromo-2-fluorobenzaldehyde | HCID 736327 | — |
| Reactant | 2-(Pyrrol-1-yl)thiobenzamide | HCID 2746696 | — |
| Reactant | 1-(5-Bromo-2-fluoro-benzylidene)-pyrrolidinium chloride | HCID 17912321 | — |
| Product | 2-{2-[(5-Bromo-2-fluoro-phenyl)-pyrrolidin-1-yl-methyl]-pyrrol-1-yl}-thiobenzamide | HCID 10139288 | — |
Reaction Steps
The preparation was carried out in accordance with general synthesis instructions 4 from 2-pyrrol-1-yl-thiobenzamide and 1-(5-bromo-2-fluoro-benzylidene)-pyrrolidinium chloride, which had been prepared in accordance with example 4 from 5-bromo-2-fluorobenzaldehyde and pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07034018B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-809a408988ba47ef917fc5d8c29386c8 |
| Source note | uspto-grants-2006_04 |