HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tartrate → HCID 77679381, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tartrate | HCID 119400 | — |
| Reactant | (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine | HCID 9834068 | — |
| Reactant | rel-(1R,2R)-2-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]cyclopentanol | HCID 87885146 | — |
| Product | HCID 77679381 | HCID 77679381 | — |
Reaction Steps
Prepared using the product from Example 13 step b) (0.15 g) and (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (0.20 g) (prepared as described in WO 9905143) by the method of Example 13, step c). Purified by chromatography (SiO2, ethyl acetate:dichloromethane 1:9 as eluant) to afford the title (0.12 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07034032B2 |
| Source dataset | uspto-grants-2006_04 |
| ORD ID | ord-9862e648a30d4c6782e8286073b8825d |
| Source note | uspto-grants-2006_04 |