4-Chlorobenzaldehyde → HCID 69592014, compound

HRID 1797086Notes

Reaction equation

HRID 1797086 reaction equation
[N+:1]1([O-:8])[C:2]([CH3:7])=[CH:3][CH:4]=[CH:5][CH:6]=1.C([O-])(C)(C)C.[K+].[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1>>[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=[CH:7][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N+:1]=2[O-:8])=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 77264-ChlorobenzaldehydeHCID 136022-Methylpyridine 1-oxideHCID 23665647Potassium tert-butoxide

Product 1

HCID 69592014HCID 69592014, compound

Procedure

Following the general method described in example 2a, 2-picoline-1-oxide was reacted with potassium tert.-butanolate and 4-chloro-benzaldehyde. After extraction and chromatography the title compound was obtained as a yellow solid material. MS: m/e=231 (M+).

Workup

  1. extractionAfter extraction and chromatography the title compound
  2. customwas obtained as a yellow solid material

Sources & evidence

ORD record
ord-11c97e291d6e4330a62718d0d55a8f42
Source dataset
uspto-grants-2006_04
Patent number
US07034044B2

Reaction notes

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