Sodium Iodide → 6-iodohexyl (2E)-3-(4-butoxy-3-methoxyphenyl)-2-propenoate

HRID 1797345Notes

Reaction equation

HRID 1797345 reaction equation
[CH2:1]([O:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]Cl)=[O:15])=[CH:8][C:7]=1[O:24][CH3:25])[CH2:2][CH2:3][CH3:4].[I-:26].[Na+]>>[CH2:1]([O:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][I:26])=[O:15])=[CH:8][C:7]=1[O:24][CH3:25])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 5238Sodium IodideHCID 865943186-chlorohexyl (2E)-3-(4-butoxy-3-methoxyphenyl)-2-propenoate

Product 1

HCID 865943196-iodohexyl (2E)-3-(4-butoxy-3-methoxyphenyl)-2-propenoate

Procedure

Preparation can be carried out analogously to Example 1 using 4.00 g (10.84 mmol) 6-chlorohexyl (2E)-3-(4-butoxy-3-methoxyphenyl)-2-propenoate and 9.75 g (65.05 mmol) sodium iodide, to yield 6-iodohexyl (2E)-3-(4-butoxy-3-methoxyphenyl)-2-propenoate.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-851207682600444aa36f74cfdcd82227
Source dataset
uspto-grants-2006_04
Patent number
US07034098B2

Reaction notes

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