Phenylhydrazine → HCID 178433621, compound

HRID 1797909Notes

Reaction equation

HRID 1797909 reaction equation
[C:1]1([N:7]2C(=O)C3=CNC4C=CC=CC=4C3=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[C:22]1[C:31]2[C:26](=[CH:27][C:28]([F:33])=[C:29]([F:32])[CH:30]=2)[N:25]=[C:24]([CH3:34])[C:23]=1[C:35]([O:37]CC)=O.C1(NN)C=CC=CC=1>>[F:33][C:28]1[C:29]([F:32])=[CH:30][C:31]2[C:22]3[C:23]([C:35](=[O:37])[N:7]([C:1]4[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=4)[N:8]=3)=[C:24]([CH3:34])[NH:25][C:26]=2[CH:27]=1

Participants

4

Reactant 3

HCID 7516PhenylhydrazineHCID 58085692HCID 58085692, compoundHCID 178515184HCID 178515184, compound

Product 1

HCID 178433621HCID 178433621, compound

Procedure

The title compound was synthesized following the procedure described in synthesis of 4a using 3i and phenyl hydrazine. 1H NMR (DMSO-d6) δ (ppm): 2.80 (3H, s), 6.87 (1H, m), 7.19 (1H, m), 7.34 (1H, m), 7.42 (1H, m), 7.61 (1H, m), 8.17 (1H, m). m/z 312.2 (MH+).

Sources & evidence

ORD record
ord-9be84998730a4eae93632660fa896125
Source dataset
uspto-grants-2013_01
Patent number
US08343957B2

Reaction notes

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