Bis(2-Methoxyethyl)amine → HCID 59436122, compound

HRID 1797951Notes

Reaction equation

HRID 1797951 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:33])[NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18]([NH:21][CH2:22][C:23]3[CH:28]=[CH:27][C:26]([S:29](=[O:32])(=[O:31])[NH2:30])=[CH:25][CH:24]=3)(=[O:20])=[O:19])=[CH:14][CH:13]=2)[CH:6]=[CH:7][CH:8]=1)#[N:2].[CH3:34][O:35][CH2:36][CH2:37][NH:38][CH2:39][CH2:40][O:41][CH3:42]>>[CH3:34][O:35][CH2:36][CH2:37][N:38]([CH2:39][CH2:40][O:41][CH3:42])[C:1](=[NH:2])[C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH:9][C:10]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18](=[O:20])(=[O:19])[NH:21][CH2:22][C:23]3[CH:28]=[CH:27][C:26]([S:29](=[O:32])(=[O:31])[NH2:30])=[CH:25][CH:24]=3)=[CH:14][CH:13]=2)=[O:33])[CH:4]=1

Participants

3

Reactant 2

HCID 2383Bis(2-Methoxyethyl)amineHCID 574961804-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamide

Product 1

HCID 59436122HCID 59436122, compoundYield 11%

Procedure

The title compound was prepared from 4-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamide following procedure C and using 1.1 equivalents of bis(2-methoxyethyl)amine as secondary amine. The product was purified by preparative HPLC.

Workup

  1. customThe product was purified by preparative HPLC

Sources & evidence

ORD record
ord-57a7946adfeb445a95a584923dc4a0bd
Source dataset
uspto-grants-2013_01
Patent number
US08343963B2

Reaction notes

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