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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1798013Generated: October 31, 2026

Indole → 1-Benzylindole

https://huagongshe.com/reaction/1798013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndoleHCID 798—
ReactantBenzyl ChlorideHCID 7503—
ReactantPotassium HydroxideHCID 14797—
SolventAcetoneHCID 180—
Product1-BenzylindoleHCID 96913—

Reaction Steps

1-benzylindole was prepared by reaction of the indole with benzyl chloride in the presence of potassium hydroxide in acetone at ambient temperature according to the procedure described in Y. Kikugawa, Y. Miyake Synthesis 1981, 461-462.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08343964B2
Source datasetuspto-grants-2013_01
ORD IDord-f476129f18d6448aa59061c7668257ce
Source noteuspto-grants-2013_01