Boronic Acid → [4-(6'-tert-Butylamino-[2,2';4',3'']terpyridin-5''-yl)-phenyl]-(4-methyl-piperazin-1-yl)-methanone

Participants

Role	Name	HCID	Charge
Reactant	Boronic Acid	HCID 61668	—
Reactant	1-(4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)piperazine	HCID 17749913	—
Reactant	[4-(6'-tert-Butylamino-[2,2';4',3'']terpyridin-5''-yl)-phenyl]-piperazin-1-yl-methanone	HCID 68762609	—
Product	[4-(6'-tert-Butylamino-[2,2';4',3'']terpyridin-5''-yl)-phenyl]-(4-methyl-piperazin-1-yl)-methanone	HCID 68763603	—

Reaction Steps

The title compound is prepared analogously to [4-(6′-tert-Butylamino-[2,2′;4′,3″]terpyridin-5″-yl)-phenyl]-piperazin-1-yl-methanone (Example 2.48) by replacing piperazin-1-yl-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanone with the appropriate boronic acid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08343966B2
Source dataset	uspto-grants-2013_01
ORD ID	ord-acdf0299bd44494bbc0f2cb404b7b056
Source note	uspto-grants-2013_01