HRID1798504

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(O)c1cc(-c2cncc(Br)c2)cc(-c2ccccn2)n1

HCID68735197

未命名化合物

结构：CNc1cc(-c2cncc(-c3cnn(C4CCN(C(C)C)CC4)c3)c2)cc(-c2ccccn2)n1

HCID86633647

未命名化合物

PRODUCTS

生成物

结构：CC(O)Cc1cc(-c2cncc(-c3cnn(C4CCN(C(C)C)CC4)c3)c2)cc(-c2ccccn2)n1

HCID86633646

未命名化合物

PROCEDURE

实验过程

is prepared analogously to (5″-[1-(1-Isopropyl-piperidin-4-yl)-1H-pyrazol-4-yl]-[2,2′;4′,3″]terpyridin-6′-yl)-methyl-amine (Example 2.175) by replacing (5″-Bromo-[2,2′;4′,3″]terpyridin-6′-yl)-methyl-amine (Example 2.1; step1) with 2-(5″-Bromo-[2,2′;4′,3″]terpyridin-6′-yl)-propan-2-ol (Example 2.80; step2)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e6bb061dbc524c63b0c39e4de54bd140
来源数据集: uspto-grants-2013_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08343966B2
来源说明: uspto-grants-2013_01

反应 SMILES

[CH:1]([N:4]1[CH2:9][CH2:8][CH:7]([N:10]2[CH:14]=[C:13]([C:15]3[CH:16]=[C:17]([C:21]4[CH:26]=[C:25](NC)[N:24]=[C:23]([C:29]5[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=5)[CH:22]=4)[CH:18]=[N:19][CH:20]=3)[CH:12]=[N:11]2)[CH2:6][CH2:5]1)([CH3:3])[CH3:2].BrC1C=C(C2C=[C:46]([C:48]([OH:51])(C)[CH3:49])N=C(C3C=CC=CN=3)C=2)C=NC=1>>[CH:1]([N:4]1[CH2:5][CH2:6][CH:7]([N:10]2[CH:14]=[C:13]([C:15]3[CH:16]=[C:17]([C:21]4[CH:26]=[C:25]([CH2:46][CH:48]([OH:51])[CH3:49])[N:24]=[C:23]([C:29]5[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=5)[CH:22]=4)[CH:18]=[N:19][CH:20]=3)[CH:12]=[N:11]2)[CH2:8][CH2:9]1)([CH3:3])[CH3:2]