2-(5''-Bromo-[2,2';4',3'']terpyridin-6'-yl)-propan-2-ol → (5''-[1-(1-Isopropyl-piperidin-4-yl)-1H-pyrazol-4-yl]-[2,2';4',3'']terpyridin-6'-yl]-propan-2-ol

Participants

Role	Name	HCID	Charge
Reactant	2-(5''-Bromo-[2,2';4',3'']terpyridin-6'-yl)-propan-2-ol	HCID 68735197	—
Reactant	(5''-[1-(1-Isopropyl-piperidin-4-yl)-1H-pyrazol-4-yl]-[2,2';4',3'']terpyridin-6'-yl)-methyl-amine	HCID 86633647	—
Product	(5''-[1-(1-Isopropyl-piperidin-4-yl)-1H-pyrazol-4-yl]-[2,2';4',3'']terpyridin-6'-yl]-propan-2-ol	HCID 86633646	—

Reaction Steps

is prepared analogously to (5″-[1-(1-Isopropyl-piperidin-4-yl)-1H-pyrazol-4-yl]-[2,2′;4′,3″]terpyridin-6′-yl)-methyl-amine (Example 2.175) by replacing (5″-Bromo-[2,2′;4′,3″]terpyridin-6′-yl)-methyl-amine (Example 2.1; step1) with 2-(5″-Bromo-[2,2′;4′,3″]terpyridin-6′-yl)-propan-2-ol (Example 2.80; step2)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08343966B2
Source dataset	uspto-grants-2013_01
ORD ID	ord-e6bb061dbc524c63b0c39e4de54bd140
Source note	uspto-grants-2013_01