反应详情

This compound is prepared analogously to Cyclopropyl-{5″-[3-(4-isopropyl-piperazin-1-yl)-prop-1-ynyl]-[2,2′;4′,3″]terpyridin-6′-yl}-amine (Example 2.127) by replacing (5″-Bromo-[2,2′;4′,3″]terpyridin-6′-yl)-cyclopropyl-amine (Example 1.26) with (5″-Bromo-[2,2′;4′,3″]terpyridin-6′-yl)-isopropyl-amine (Example 2.46, step1) and by replacing 1-isopropyl-4-(prop-2-ynyl)piperazine (Intermediate D1) with 1-tert-Butyl-4-prop-2-ynyl-piperazine (Intermediate D2).