1-(Prop-2-YN-1-YL)-4-(propan-2-YL)piperazine → {5''-[3-(4-Isopropyl-piperazin-1-yl)-prop-1-ynyl]-[2,2';4',3'']terpyridin-6'-yl}-methyl-amine

Participants

Role	Name	HCID	Charge
Reactant	1-(Prop-2-YN-1-YL)-4-(propan-2-YL)piperazine	HCID 58366557	—
Reactant	Methyl-[5''-(3-methyl-3H-imidazol-4-ylethynyl)-[2,2';4',3'']terpyridin-6'-yl]-amine	HCID 86633650	—
Product	{5''-[3-(4-Isopropyl-piperazin-1-yl)-prop-1-ynyl]-[2,2';4',3'']terpyridin-6'-yl}-methyl-amine	HCID 86633652	—

Reaction Steps

This compound is prepared analogously to Methyl-[5″-(3-methyl-3H-imidazol-4-ylethynyl)-[2,2′;4′,3″]terpyridin-6′-yl]-amine (Example 2.182) by replacing 1-methyl-5-((trimethylsilyl)ethynyl)-1H-imidazole with 1-isopropyl-4-(prop-2-ynyl)piperazine (Intermediate D1)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08343966B2
Source dataset	uspto-grants-2013_01
ORD ID	ord-9894fb0d0ac84006be010398259c70d8
Source note	uspto-grants-2013_01