HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)phenyl isocyanate → HCID 58941068, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)phenyl isocyanate | HCID 9483 | — |
| Reactant | Methyl (2E)-3-{3-fluoro-2-[(triphenylphosphoranylidene)amino]phenyl}propenoate | HCID 11983908 | — |
| Reactant | 8-Fluoro-1,2,3,4-tetrahydropyrazino[1,2-a]indole | HCID 45115769 | — |
| Product | HCID 58941068 | HCID 58941068 | — |
Reaction Steps
Starting with 546 mg (1.2 mmol) of the iminophosphorane from Example 12A, 402 mg (1.2 mmol) of 1-isocyanato-3-(trifluoromethyl)benzene and 240 mg (1.3 mmol) of 8-fluoro-1,2,3,4-tetrahydropyrazino[1,2-a]indole from Example 36A, the general procedure [M] gives 610 mg (86% of theory) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08343981B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-83a4b1fafd154fff8251b447b60ac6c6 |
| Source note | uspto-grants-2013_01 |