2-Aminothiazole → HCID 178458559, compound

Participants

Reaction Steps

Compound of Production Example 151 can be produced by the same method as Production Example 1, by a method according thereto, or by a combination of these and ordinary methods, with the use of 3,6-dichloro-2-pyridinecarboxylic acid, 2-amino-thiazole, 4-(1,1-dimethyl-1-hydroxymethyl)-thiophenol and 3-mercapto-1,2,4-triazole. 1HNMR (CDC3) δ: 1.63 (6H, s), 6.99-7.03 (2H, m), 7.18 (1H, d, J=8.4 Hz), 7.39 (1H, d, J=3.6 Hz), 7.51 (2H, d, J=8.4 Hz), 7.58 (2H, d, J=8.4 Hz), 8.30 (1H, s) ESI-MS (m/e): 471 [M+H]+

Provenance & Evidence