HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Cyclopropylethoxy)-n-((z)-2-[4-(cyclopropyloxy)phenyl]-1-{[(2-hydroxyethyl)amino]carbonyl}vinyl)benzamide → 4-(2-Cyclopropylethoxy)-n-{1-[4-(cyclopropyloxy)benzyl]-2-[(2-hydroxyethyl)amino]-2-oxoethyl}benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Cyclopropylethoxy)-n-((z)-2-[4-(cyclopropyloxy)phenyl]-1-{[(2-hydroxyethyl)amino]carbonyl}vinyl)benzamide | HCID 57684491 | — |
| Reactant | 4-(2-Cyclopropylethoxy)-n-[2-[(2-hydroxyethyl)amino]-2-oxo-1-(4-propylbenzyl)ethyl]benzamide | HCID 57972150 | — |
| Product | 4-(2-Cyclopropylethoxy)-n-{1-[4-(cyclopropyloxy)benzyl]-2-[(2-hydroxyethyl)amino]-2-oxoethyl}benzamide | HCID 57972156 | 60.4% |
Reaction Steps
A reaction similar to that described in Example (1 (1e) was conducted using 4-(2-cyclopropylethoxy)-N-((Z)-2-[4-(cyclopropyloxy)phenyl]-1-{[(2-hydroxyethyl)amino]carbonyl}vinyl)benzamide (193 mg) to give 117 mg of the title compound (white powder).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344029B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-03b3f2dfa9394366a900a83fc5018850 |
| Source note | uspto-grants-2013_01 |