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HRID 1799275作成日:2026年10月26日

4-(4-(Trifluoromethyl)phenoxy)benzoic acid → 2-{[(2S)-3-[4-(Trifluoromethoxy)phenyl]-2-({4-[4-(trifluoromethyl)phenoxy]benzoyl}amino)propanoyl]amino}ethyl acetate

https://huagongshe.com/reaction/1799275

反応式

関与物質

役割名称HCID仕込み量
反応物4-(4-(Trifluoromethyl)phenoxy)benzoic acidHCID 3673481—
反応物2-({(2S)-2-amino-3-[4-(trifluoromethoxy)phenyl]propanoyl}amino)ethyl acetateHCID 69017543—
生成物2-{[(2S)-3-[4-(Trifluoromethoxy)phenyl]-2-({4-[4-(trifluoromethyl)phenoxy]benzoyl}amino)propanoyl]amino}ethyl acetateHCID 86636530—

反応手順

A reaction similar to that described in Example 50 was conducted using 2-({(2S)-2-amino-3-[4-(trifluoromethoxy)phenyl]propanoyl}amino)ethyl acetate and 4-[4-(trifluoromethyl)phenoxy]benzoic acid used in Example 41 (41a) to give the title compound.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08344029B2
出典データセットuspto-grants-2013_01
ORD IDord-acb4ef0b838949ef99a5959908f8b788
出典メモuspto-grants-2013_01