HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-({(2S)-2-amino-3-[4-(trifluoromethyl)phenyl]propanoyl}amino)ethyl acetate → 2-({(2S)-2-({4-[4-(Trifluoromethyl)phenoxy]benzoyl}amino)-3-[4-(trifluoromethyl)phenyl]propanoyl}amino)ethyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-({(2S)-2-amino-3-[4-(trifluoromethyl)phenyl]propanoyl}amino)ethyl acetate | HCID 69017874 | — |
| Reactant | 4-[1-(Trifluoromethyl)phenoxy]benzoic acid | HCID 69019590 | — |
| Product | 2-({(2S)-2-({4-[4-(Trifluoromethyl)phenoxy]benzoyl}amino)-3-[4-(trifluoromethyl)phenyl]propanoyl}amino)ethyl acetate | HCID 86636531 | — |
Reaction Steps
A reaction similar to that described in Example 50 was conducted using 2-({(2S)-2-amino-3-[4-(trifluoromethyl)phenyl]propanoyl}amino)ethyl acetate and 4-[1-(trifluoromethyl)phenoxy]benzoic acid used in Example 41 (41a) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08344029B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-39824624b02a42309c5f8df1a846a58a |
| Source note | uspto-grants-2013_01 |