HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(4,4,4-Trifluorobutoxy)benzoic acid → 2-{[4-(4,4,4-Trifluorobutoxy)benzoyl]amino}-3-[4-(trifluoromethoxy)phenyl]propanoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(4,4,4-Trifluorobutoxy)benzoic acid | HCID 22361401 | — |
| Edukt | 2-Amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid hydrochloride | HCID 22603340 | — |
| Produkt | 2-{[4-(4,4,4-Trifluorobutoxy)benzoyl]amino}-3-[4-(trifluoromethoxy)phenyl]propanoic acid | HCID 78068622 | 95% |
Reaktionsschritte
A reaction similar to that described in Example 70 (70a) was conducted using 4-(4,4,4-trifluorobutoxy)benzoic acid (6.21 g) prepared in Example 81 (81a) and 2-amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid hydrochloride (7.20 g) prepared in Reference Example 2 to give 11.4 g of the title compound (white powder).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08344029B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-3d24bff01c6b4d958910a9ee0312b3a9 |
| Quellennotiz | uspto-grants-2013_01 |